Code
OSG00011G
$240USD
ID Tag
Rb654-060908-G
Immunogen
A synthetic peptide to phospho S41 of human Axonal membrane protein GAP-43 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in many species including rat, mouse and zebrafish.
Accession
Also known
Neuromodulin, growth-associated protein 43, protein F1, Basp2, B-50
Target
FUNCTION: This protein is associated with nerve growth. It is a major component of the motile "growth cones" that form the tips of elongating axons.
SUBUNIT: Binds calmodulin with a greater affinity in the absence of Ca(2+) than in its presence.
SUBCELLULAR LOCATION: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, growth cone membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, synapse. Note: Cytoplasmic surface of growth cone and synaptic plasma membranes.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Cimler B.M, et al. J. Biol. Chem. 262:12158-12163(1987).
2. Ballif B.A, et al. Mol. Cell. Proteomics 3:1093-1101(2004).
Limitation
For research use only
Related
products
Code
OSG00011G
$240USD
Unit size
500 µg
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
IgG
Clonality
Polyclonal
Isotype
Polyclonal, IgG
Applications
IHC, WB. Use at a concentration of 10-50 µg/ml. The optimal working concentration should be determined by the end user. Not yet tested in other applications. This antibody may also recognise the unphosphorylated form.
Specificity
Specific for GAP-43.
Spcs X-react.
Human, rat, mouse. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.