A synthetic peptide from aa region 350-400 of mouse MAP2 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat.
Microtubule-associated protein 2, MAP 2, MAP-2, MAP2R
Regulates and organizes microtubules; may serve as a scaffolding protein for neuromodulatory activities.
FUNCTION: The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
DEVELOPMENTAL STAGE: Isoform MAP2C is expressed during embryonic brain development and until postanatal day 10. Isoform MAP2B is expressed throughout brain development.
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
12 months after reconstitution
This item will be shipped to you at ambient temperature in a lyophilised form.
1. Kindler S, et al. Nucleic Acids Res. 18:2822-2822(1990).
2. Kindler S, et al. J. Biol. Chem. 265:19679-19684(1990).
For research use only
NZ white rabbit
IHC, WB. A working concentration of 10-50 µg/ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
Specific for MAP-2.
Rat, mouse. Other species not yet tested.
Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.