⚬ Services
Code
OSK00071W
$240USD    Buy Now 

ID Tag
Rb2215-201113-WS

Immunogen
A synthetic peptide from aa region 60-120 of mouse KCNQ3 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in human and rat.

Accession

Also known
Potassium voltage-gated channel subfamily KQT member 3, Voltage-gated potassium channel subunit Kv7.3, Potassium channel subunit alpha KvLQT3, KQT-like 3

Target
Function: Probably important in the regulation of neuronal excitability. Associates with KCNQ2 or KCNQ5 to form a potassium channel with essentially identical properties to the channel underlying the native M-current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons as well as the responsiveness to synaptic inputs.
Tissue specificity: Predominantly expressed in brain. Expressed in brain and sympathetic ganglia. In brain, expressed in cortex, hippocampus and at much lower levels in cerebellum. In sympathetic ganglia, expressed at approximately equal levels in both superior cervical ganglia and prevertebral ganglia.
Subcellular location: Membrane; Multi-pass membrane protein.

Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date
12 months after reconstitution

Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.

References
1. Schroeder B.C, et al. Nature 396:687-690(1998)

Limitation
For research use only

Related
products

Code
OSK00071W
$240USD    Buy Now 

Unit size
100 ul

Conjugate
Unconjugated antibody

Host
NZ white rabbit

Purity
Whole serum

Clonality
Polyclonal

Isotype
Polyclonal, whole serum

Applications
IHC, WB (confirmed by recombinant protein). A dilution of 1 : 200 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity
Specific for KCNQ3.

Spcs X-react.
Human, rat, mouse. Other species not yet tested.

Format
Lyophilised

Reconstitution
Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.

Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

⚬ Products
Rabbit antibody to KCNQ3 (60-120)
Content

Download Protocols

APES coating of slides
Loading Buffer: Reducing
IHC-P on Autostainer
G1 Lysing Buffer
WB Protocol online
IHC-P HIER (Tris-EDTA, pH 9)
4% PFA
Davidson's fix (modified)
....Tissue lysate perparation
....G2 Lysing Buffer
....R Lysing Buffer
....G3 Lysing Buffer
....G4 Lysing Buffer
....G5 Lysing Buffer
....G6 Lysing Buffer
Content

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