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Code
OSG00025W
$240USD
ID Tag
Sh99-060908-WS
Immunogen
A synthetic peptide to phospho S41 of human Axonal membrane protein GAP-43 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in rat, mouse, zebra fish and chicken.
Accession
Also known
Neuromodulin, growth-associated protein 43, protein F1, Basp2, B-50
Target
FUNCTION: This protein is associated with nerve growth. It is a major component of the motile "growth cones" that form the tips of elongating axons.
SUBUNIT: Binds calmodulin with a greater affinity in the absence of Ca(2+) than in its presence.
SUBCELLULAR LOCATION: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, growth cone membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, synapse. Note: Cytoplasmic surface of growth cone and synaptic plasma membranes.
SUBUNIT: Binds calmodulin with a greater affinity in the absence of Ca(2+) than in its presence.
SUBCELLULAR LOCATION: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, growth cone membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, synapse. Note: Cytoplasmic surface of growth cone and synaptic plasma membranes.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Cimler B.M, et al. J. Biol. Chem. 262:12158-12163(1987).
2. Ballif B.A, et al. Mol. Cell. Proteomics 3:1093-1101(2004).
3. Vosseller K, et al. Proteomics 5:388-398(2005).
2. Ballif B.A, et al. Mol. Cell. Proteomics 3:1093-1101(2004).
3. Vosseller K, et al. Proteomics 5:388-398(2005).
Limitation
For research use only
Related
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Code
OSG00025W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
Sheep
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. This antibody may also recognise the unphosphorylated form.
Specificity
Specific for GAP-43.
Spcs X-react.
Human, rat, mouse. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSG00025W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
Code
OSG00025W
$240USD
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WB on rat brain lysate using Sheep antibody to phospho S41 GAP 43 (OSG00025W) at 1 : 1000 dilution incubated overnight at 4°C. Pre-absorption of the antibody with the immunising peptide completely abolishes the detected band. |
⚬ Products
Sheep antibody to phospho S41 GAP 43
