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Code
OSB00009W
$240USD
ID Tag
Rb1482-120610-WS
Immunogen
A synthetic peptide from n-terminal region of mouse BEX3 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat.
Accession
Also known
Protein BEX3, NGFRAP1, p75NTR-associated cell death executor, Nerve growth factor receptor-associated protein 1 (TNFRSF16) associated protein 1, Ovarian granulosa cell 13.0 kDa protein HGR74, NADE
Target
FUNCTION: May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death. Binds transition metals. This protein is probably ubiquitinated and is degraded by the proteasome.
SUBUNIT: Self-associates. Binds to the DEATH domain of p75NTR/NGFR. Interacts with 14-3-3 epsilon. Interacts with DIABLO/SMAC.
SUBCELLULAR LOCATION: Nucleus. Cytoplasm. Note: Shuttles between the cytoplasm and the nucleus. Associates with replicating mitochondria.
TISSUE SPECIFICITY: widely expressed. In cochlea, it is expressed in pillar cells from postnatal day 2 to adulthood.
SUBUNIT: Self-associates. Binds to the DEATH domain of p75NTR/NGFR. Interacts with 14-3-3 epsilon. Interacts with DIABLO/SMAC.
SUBCELLULAR LOCATION: Nucleus. Cytoplasm. Note: Shuttles between the cytoplasm and the nucleus. Associates with replicating mitochondria.
TISSUE SPECIFICITY: widely expressed. In cochlea, it is expressed in pillar cells from postnatal day 2 to adulthood.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Mukai J, et al. J. Biol. Chem. 275:17566-17570(2000).
2. Alvarez E, et al. Gene 357:18-28(2005).
2. Alvarez E, et al. Gene 357:18-28(2005).
Limitation
For research use only
Related
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Code
OSB00009W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user.
Specificity
Specific for BEX3.
Spcs X-react.
Rat, mouse. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSB00009W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
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Rabbit antibody to BEX3
