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Code
OSB00001G
$240USD
ID Tag
Sh0277-220318-G
Immunogen
A synthetic peptide from human Beclin-1 conjugated to blue carrier protein has been used as the antigen. The antigen is homologous in rat and mouse.
Accession
Also known
Beclin-1, BECN1, GT197, ATG6, VPS30, beclin1
Target
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. It may play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus. May play a role in autophagy.
SUBCELLULAR LOCATION: Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Note: Expressed in dendrites and cell bodies of cerebellar Purkinje cells
TISSUE SPECIFICITY: Ubiquitous
SUBCELLULAR LOCATION: Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Note: Expressed in dendrites and cell bodies of cerebellar Purkinje cells
TISSUE SPECIFICITY: Ubiquitous
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Feng W, et al. J. Mol. Biol. 372 (1), 223-235(2007).
Limitation
For research use only
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Code
OSB00001G
$240USD
Unit size
500 µg
Conjugate
Unconjugated antibody
Host
Sheep
Purity
IgG
Clonality
Polyclonal
Isotype
IgG
Applications
IHC, WB. Use at a concentration of 10-50 µg/ml. The optimal working concentration should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for Beclin-1.
Spcs X-react.
Human, marmoset, mouse, rat. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSB00001G
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Sheep antibody to Beclin 1
