A synthetic peptide from aa region 250-300 of rat MRGPRA conjugated to blue carrier protein was used as the antigen.
Nuclear receptor MrgA10 RF-amide G protein-coupled receptor, Mrga10, MrgA, Mrgpra, MGC108580
FUNCTION: Orphan receptor activated by a subset of RFamide-family neuropeptides such as FLRF-amide and FMRF-amide. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. May regulate the function of nociceptive neurons by modulation of pain perception.
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Expressed in a subset of IB4-positive small diameter nociceptive dorsal root neurons.
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
12 months after reconstitution
This item will be shipped to you at ambient temperature in a lyophilised form.
1. Bender E, et al. Proc. Natl. Acad. Sci. U.S.A. 99:8573-8578(2002).
For research use only
NZ white rabbit
Polyclonal, whole serum
IHC, WB. A dilution of 1 : 4000 for WB on rat lysates is recommended and for mouse tissue lysates 1 : 2000 i; 1:1000 for IHC-P. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specific for MRGPRA.
Rat, mouse. Other species not yet tested.
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.