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Code
OST00437G
$240USD
ID Tag
OSX14 clone
Immunogen
Integrin alpha 4
Accession
Also known
CD49 antigen-like family member D, ITGA4, CD49D
Target
FUNCTION: Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells.
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Takada Y, et al. EMBO J. 8:1361-1368(1989)
Limitation
For research use only
Code
OST00437G
$240USD
Unit size
150 µg
Conjugate
Unconjugated antibody
Host
Mouse
Purity
IgG
Clonality
Monoclonal
Isotype
IgG2bκ
Applications
IHC. A dilution of 1 : 500 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not tested in other applications.
Specificity
Specific for Integrin α4
Spcs X-react.
Human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 150 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OST00437G
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Mouse monoclonal to Integrin α4: OSX14 clone
