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Code
OSF00028W
$240USD
ID Tag
Rb2294-150114-WS
Immunogen
A synthetic peptide from aa region 775-816 of hydra FGFR conjugated to blue carrier protein was used as the antigen.
Accession
Also known
Fibroblast growth factor receptor, Protein kringelchen
Target
FUNCTION: Receptor for basic fibroblast growth factor.
SUBCELLULAR LOCATION: Membrane; Single-pass membrane protein
Developmental stage: During tissue displacement in the early bud, transiently present ubiquitously. A few hours later, coincident with the acquisition of organiser properties by the bud tip, a few cells in the apical tip express the gene strongly. About 20 hours after the onset of evagination, expression is switched on in a ring of cells surrounding the bud base, and shortly thereafter vanishes from the apical expression zone. The basal ring persists in the parent during tissue contraction and foot formation in the young polyp, until several hours after bud detachment. Inhibition of bud detachment by head regeneration results in severe distortion, disruption or even complete loss of the well-defined ring-like expression zone.
SUBCELLULAR LOCATION: Membrane; Single-pass membrane protein
Developmental stage: During tissue displacement in the early bud, transiently present ubiquitously. A few hours later, coincident with the acquisition of organiser properties by the bud tip, a few cells in the apical tip express the gene strongly. About 20 hours after the onset of evagination, expression is switched on in a ring of cells surrounding the bud base, and shortly thereafter vanishes from the apical expression zone. The basal ring persists in the parent during tissue contraction and foot formation in the young polyp, until several hours after bud detachment. Inhibition of bud detachment by head regeneration results in severe distortion, disruption or even complete loss of the well-defined ring-like expression zone.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Sudhop S, et al. Development 131:4001-4011(2004)
Limitation
For research use only
Code
OSF00028W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB (confirmed by recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for FGFR.
Spcs X-react.
Hydra. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSF00028W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to hydra FGFR (775-816)
