⚬ Services
Code
OSS00392W
$240USD    Buy Now 

ID Tag
Rb2202-201113-WS

Immunogen
A synthetic peptide from aa region 50-100 of mouse SMN1 conjugated to blue carrier protein was used as the antigen.

Accession

Also known
Survival motor neuron protein, Gemin 1

Target
The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. It may also play a role in the metabolism of snoRNPs. Required in motor neurons and proprioceptive neurons to ensure correct U12 intron splicing and proper levels of Tmem41b mRNA. Required for normal motor neuron development.
Subcellular location: Cytoplasm. Nucleus gem. Cytoplasmic granule. Cytoplasm  myofibril sarcomere Z line. Note: Under stress conditions colocalizes with Rpp20/Pop7 in punctuated cytoplasmic granules. Colocalizes with Actn at the Z-line of skeletal muscle.

Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date
12 months after reconstitution

Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.

References
1. Schrank B, et al. Proc. Natl. Acad. Sci. U.S.A. 94:9920-9925(1997)

Limitation
For research use only

Related
products

Code
OSS00392W
$240USD    Buy Now 

Unit size
100 ul

Conjugate
Unconjugated antibody

Host
NZ white rabbit

Purity
Whole serum

Clonality
Polyclonal

Isotype
Polyclonal, whole serum

Applications
IHC, WB (confirmed by recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity
Specific for SMN1.

Spcs X-react.
Mouse. Other species not yet tested.

Format
Lyophilised

Reconstitution
Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.

Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

⚬ Products
Rabbit antibody to SMN1 (50-100)
Content

Download Protocols

APES coating of slides
Loading Buffer: Reducing
IHC-P on Autostainer
G1 Lysing Buffer
WB Protocol online
IHC-P HIER (Tris-EDTA, pH 9)
4% PFA
Davidson's fix (modified)
....Tissue lysate perparation
....G2 Lysing Buffer
....R Lysing Buffer
....G3 Lysing Buffer
....G4 Lysing Buffer
....G5 Lysing Buffer
....G6 Lysing Buffer
Content

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