AIP1 antibody, MAGI2 antibody

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSA00244W

$240USD

ID Tag

Rb2155-011013-WS

Immunogen

A synthetic peptide from aa region 1260-1310 of human AIP1 conjugated to an immunogenic carrier protein was used as the antigen.

Accession

AIP1_HUMAN

Also known

Membrane associated guanylate kinase, WW and PDZ domain containing protein 2, Atrophin 1 interacting protein 1, AIP-1, Atrophin 1 interacting protein A, Membrane-associated guanylate kinase inverted 2, MAGI-2, MAGI2, ACVRINP1

Target

FUNCTION: Seems to act as scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins. May play a role in regulating activin-mediated signaling in neuronal cells. Enhances the ability of PTEN to suppress AKT1 activation. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth.
SUBCELLULAR LOCATION: Cytoplasm. Late endosome. Cell junction âº synapse âº synaptosome. Cell membrane; Peripheral membrane protein. Note: Localized diffusely in the cytoplasm before nerve growth factor (NGF) stimulation. Recruted to late endosomes after NGF stimulation. Membrane-associated in synaptosomes.
TISSUE SPECIFICITY: Specifically expressed in brain.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Wood J.D, et al. Mol. Cell. Neurosci. 11:149-160(1998)

Limitation

For research use only

Code

OSA00244W

$240USD

Unit size

100 µl

Conjugate

Unconjugated antibody

Host

NZ white rabbit

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity

Specific for AIP1.

Spcs X-react.

Human. Other species not yet tested.

Format

Lyophilised

Reconstitution

Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OSA00244W