ABCC9 antibody, SUR2 antibody

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSA00226W

$240USD

ID Tag

Rb1971-091212-WS

Immunogen

A synthetic peptide from aa region 600-700 of human ABCC9 conjugated to an immunogenic carrier protein was used as the antigen.

Accession

ABCC9_HUMAN

Also known

ATP-binding cassette sub-family C member 9, Sulfonylurea receptor 2, SUR2

Target

FUNCTION: Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with KCNJ11. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation.
Defects in ABCC9 are the cause of cardiomyopathy dilated type 1O (CMD1O).
Defects in ABCC9 are the cause of familial atrial fibrillation type 12 (ATFB12).
Defects in ABCC9 are the cause of hypertrichotic osteochondrodysplasia (HTOCD).
Subcellular location: Membrane; Multi-pass membrane protein.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Allebrandt K.V, et al. Mol. Psychiatry 0:0-0(2011)
2. Harakalova M, et al. Nat. Genet. 44:793-796(2012)

Limitation

For research use only

Code

OSA00226W

$240USD

Unit size

100 µl

Conjugate

Unconjugated antibody

Host

NZ white rabbit

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB (recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity

Specific for ABCC9.

Spcs X-react.

Human. Other species not yet tested.

Format

Lyophilised

Reconstitution

Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OSA00226W