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Code
OSA00225W
$240USD    Buy Now 

ID Tag
Rb1970-091212-WS

Immunogen
A synthetic peptide from aa region 1500-1581 of human ABCC8 conjugated to blue carrier protein was used as the antigen.

Accession

Also known
ATP-binding cassette sub-family C member 8, Sulfonylurea receptor 1, HRINS, SUR, SUR1

Target
FUNCTION: Putative subunit of the beta-cell ATP-sensitive potassium channel (KATP). Regulator of ATP-sensitive K+ channels and insulin release.
Defects in ABCC8 are a cause of leucine-induced hypoglycemia (LIH).
Defects in ABCC8 are a cause of diabetes mellitus permanent neonatal (PNDM).
Defects in ABCC8 are the cause of transient neonatal diabetes mellitus type 2 (TNDM2).
Subcellular location: Membrane; Multi-pass membrane protein.

Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date
12 months after reconstitution

Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.

References
1. Thomas P.M, et al. Science 268:426-429(1995)

Limitation
For research use only

Code
OSA00225W
$240USD    Buy Now 

Unit size
100 µl

Conjugate
Unconjugated antibody

Host
NZ white rabbit

Purity
Whole serum

Clonality
Polyclonal

Isotype
Polyclonal, whole serum

Applications
IHC, WB (recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity
Specific for ABCC8.

Spcs X-react.
Human. Other species not yet tested but expected to work in mouse and rat.

Format
Lyophilised

Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

⚬ Products
Rabbit antibody to ABCC8
Content

Download Protocols

APES coating of slides
Loading Buffer: Reducing
IHC-P on Autostainer
G1 Lysing Buffer
WB Protocol online
IHC-P HIER (Tris-EDTA, pH 9)
4% PFA
Davidson's fix (modified)
....Tissue lysate perparation
....G2 Lysing Buffer
....R Lysing Buffer
....G3 Lysing Buffer
....G4 Lysing Buffer
....G5 Lysing Buffer
....G6 Lysing Buffer
Content

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