Kv12.3 antibody, KCNH4 antibody, Elk3 antibody, Elk1 antibody

Primary Antibodies

ABC Transporters

Autophagy

Cancer

Cellular

G Protein Signaling

Hydra Proteins

Immunology

Ion Channels & pumps

Microbiology

Neuroscience

Reporter Genes & Tags

Reproduction

SLC & Regulators

Subcellular Markers

Toxins

Peptides

Histology / Detection

⚬ Services

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSP00163W

$240USD

ID Tag

Rb1659-211110-WS

Immunogen

A synthetic peptide from c-terminal region of human KCNH4 (Kv12.3) conjugated to an immunogenic carrier protein was used as the antigen.

Accession

KCNH4_HUMAN
KCNH4_RAT
KCNH4_MOUSE

Also known

Potassium voltage-gated channel subfamily H member 4, Brain-specific eag-like channel 2, BEC2, Ether-a-go-go-like potassium channel 1, ELK channel 1, ELK1, Voltage-gated potassium channel subunit Kv12.3, Elk3

Target

Function: Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits an outward current, but shows no inactivation. Channel properties may be modulated by cAMP and subunit assembly.
Subcellular location: Membrane; Multi-pass membrane protein.
Tissue specificity: Detected only in brain, in particular in the telencephalon. Detected in putamen and caudate nucleus, and at lower levels in cerebral cortex, occipital and hippocampus.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Miyake A, et al. J. Biol. Chem. 274:25018-25025(1999)
2. Sjoeblom T, et al. Science 314:268-274(2006)

Limitation

For research use only

Code

OSP00163W

$240USD

Unit size

100 µl

Conjugate

Unconjugated antibody

Host

NZ white rabbit

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB (confirmed by recombinant protein). A dilution of 1 : 200 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity

Specific for KCNH4.

Spcs X-react.

Human, rat, mouse. Other species not yet tested.

Format

Lyophilised

Reconstitution

Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OSP00163W