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Code
OSA00158W
$240USD
ID Tag
Rb1708-021210-WS
Immunogen
A synthetic peptide from the n-terminal region of mouse Aldehyde dehydrogenase 3 (ALDH3A1) conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
AL3A1, Aldehyde dehydrogenase, dimeric NADP-preferring, Aldehyde dehydrogenase 4, Dioxin-inducible aldehyde dehydrogenase 3, Aldh3a1, Ahd-4, Ahd4, Aldh3, Aldh4
Target
ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes.
Catalytic activity: An aldehyde + NAD(P)+ + H2O = an acid + NAD(P)H.
Subcellular location: Cytoplasm.
Tissue specificity: High levels in stomach, esophagus and lung; low level in the liver and kidney. Constitutively expressed in cornea, stomach, skin, bladder and lungs. Lowest expression levels in lungs and bladder.
Catalytic activity: An aldehyde + NAD(P)+ + H2O = an acid + NAD(P)H.
Subcellular location: Cytoplasm.
Tissue specificity: High levels in stomach, esophagus and lung; low level in the liver and kidney. Constitutively expressed in cornea, stomach, skin, bladder and lungs. Lowest expression levels in lungs and bladder.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Vasiliou V, et al. Pharmacogenetics 3:281-290(1993)
2. Shiao T, et al. Pharmacogenetics 9:145-153(1999)
3. Nees D.W, et al. Mol. Cell. Biol. 22:849-855(2002)
2. Shiao T, et al. Pharmacogenetics 9:145-153(1999)
3. Nees D.W, et al. Mol. Cell. Biol. 22:849-855(2002)
Limitation
For research use only
Code
OSA00158W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for ALDH3A1.
Spcs X-react.
Mouse. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of MQ water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSA00158W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to ALDH3A1
