NPFF1 receptor antibody

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSN00065W

$240USD

ID Tag

Rb1710-021210-WS

Immunogen

A synthetic peptide from aa regio 2-43 (extracellular domain) of rat Neuropeptide FF receptor 1 conjugated to an immunogenic carrier protein was used as the antigen.

Accession

NPFFR_RAT

Also known

Neuropeptide FF receptor 1, G-protein coupled receptor 147

Target

Function: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Tissue specificity: Expressed at high levels in the hypothalamus. Moderate levels found in the midbrain, thalamus, medulla oblongata, testis, eye, whole brain, cerebral cortex, striatum, hippocampus, cerebellum, optic nerve, placenta, spinal cord, pituitary gland and ovary.
Subcellular location: Cell membrane; Multi-pass membrane protein.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Hinuma S, et al. Nat. Cell Biol. 2:703-708(2000)
2. Bonini J.A, et al. J. Biol. Chem. 275:39324-39331(2000)

Limitation

For research use only

Code

OSN00065W

$240USD

Unit size

100 µl

Conjugate

Unconjugated antibody

Host

NZ white rabbit

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB (confirmed by recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user.

Specificity

Specific for NPFF1.

Spcs X-react.

Rat. Other species not yet tested.

Format

Lyophilised

Reconstitution

Reconstitute in 100 µl of MQ water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OSN00065W