⚬ Services
Code
OSC00244W
$240USD    Buy Now 

ID Tag
Rb1682-021210-WS

Immunogen
A synthetic peptide from aa region 20-70 of mouse ABCC7 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in rat and shares 95% with human sequence.

Accession

Also known
Cystic fibrosis transmembrane conductance regulator, Channel conductance-controlling ATPase, cAMP-dependent chloride channel, ATP-binding cassette transporter sub-family C member 7, CFTR

Target
FUNCTION: Involved in the transport of chloride ions. May regulate bicarbonate secretion and salvage in epithelial cells by regulating the SLC4A7 transporter. Defects in CFTR are the cause of congenital bilateral absence of the vas deferens (CBAVD). CBAVD is an important cause of sterility in men and could represent an incomplete form of cystic fibrosis, as the majority of men suffering from cystic fibrosis lack the vas deferens.
Subcellular location: Membrane, Multi-pass membrane protein.
Tissue specificity: Found on the surface of the epithelial cells that line the lungs and other organs.

Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date
12 months after reconstitution

Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.

References
1. Denamur E, et al. Hum. Mol. Genet. 3:1089-1094(1994)
2. Delaney S.J, et al. Nat. Genet. 4:426-431(1993)

Limitation
For research use only

Code
OSC00244W
$240USD    Buy Now 

Unit size
100 µl

Conjugate
Unconjugated antibody

Host
NZ white rabbit

Purity
Whole serum

Clonality
Polyclonal

Isotype
Polyclonal, whole serum

Applications
IHC, WB (confirmed by recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity
Specific for ABCC7.

Spcs X-react.
Mouse, rat. Other species not yet tested but expected to work in human.

Format
Lyophilised

Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

⚬ Products
Rabbit antibody to ABCC7 (CFTR, 20-70)
Content

Download Protocols

APES coating of slides
Loading Buffer: Reducing
IHC-P on Autostainer
G1 Lysing Buffer
WB Protocol online
IHC-P HIER (Tris-EDTA, pH 9)
4% PFA
Davidson's fix (modified)
....Tissue lysate perparation
....G2 Lysing Buffer
....R Lysing Buffer
....G3 Lysing Buffer
....G4 Lysing Buffer
....G5 Lysing Buffer
....G6 Lysing Buffer
Content

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