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Code
OSM00101W
$260USD
ID Tag
Rb1591-120910-WS
Immunogen
A synthetic peptide from aa region 700-740 of human Mitofusin 1 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and mouse.
Accession
Also known
Transmembrane GTPase MFN1, MFN1
Target
FUNCTION: Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN1 acts independently of the cytoskeleton. Overexpression induces the formation of mitochondrial networks.
MFN1 deficient mice die early during embryonic development, due to altered mitochondria morphology, which are fragmented, showing that mitochondrial fusion is essential for embryonic development.
SUBCELLULAR LOCATION: Mitochondrion outer membrane; Multi-pass membrane protein
Tissue specificity: Widely expressed
MFN1 deficient mice die early during embryonic development, due to altered mitochondria morphology, which are fragmented, showing that mitochondrial fusion is essential for embryonic development.
SUBCELLULAR LOCATION: Mitochondrion outer membrane; Multi-pass membrane protein
Tissue specificity: Widely expressed
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Santel A, et al. J. Cell Sci. 114:867-874(2001)
Limitation
For research use only
Code
OSM00101W
$260USD
Unit size
100 ul
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB (confirmed by recombinant protein). A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for Mitofusin-1.
Spcs X-react.
Human, rat, mouse. Not yet tested in other species.
Format
Lyophilised
Reconstitution
Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSM00101W
$260USD
PDF Data Sheet
- Click to download the Data SheetMSDS
Code
OSM00101W
$260USD
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IHC on paraffin sections of human colon using Mitofusin 1 (700-740) (OSM00101W). HIER: 1 mM EDTA, pH 8 for 20 min using Thermos PT Module Detection was done using Novolink HRP polymer from Leica following manufacturer's instruction. Primary antibody: dilution 1: 1000, incubated 30 min at RT (using Autostainer) Sections were counterstained with Harris Hematoxylin. |
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IHC on paraffin sections of human colon using Mitofusin 1 (700-740) (OSM00101W). HIER: 1 mM EDTA, pH 8 for 20 min using Thermos PT Module Detection was done using Novolink HRP polymer from Leica following manufacturers instruction. Primary antibody: dilution 1: 1000, incubated 30 min at RT (using Autostainer) Sections were counterstained with Harris Hematoxylin. |
⚬ Products
Rabbit antibody to Mitofusin 1 (700-740)
