Anti MPR 300 antibody, anti M6PR antibody, anti CD222 antibody

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSM00084W

$240USD

ID Tag

Rb1436-250410-WS

Immunogen

A synthetic peptide from mouse MPR 300 conjugated to blue carrier protein was used as the antigen.

Accession

MPRI_MOUSE
MPRI_RAT

Also known

CI Man-6-P receptor, CI-MPR, M6PR, Insulin-like growth factor 2 receptor, Insulin-like growth factor II receptor, IGF-II receptor, M6P/IGF2 receptor, M6P/IGF2R, 300 kDa mannose 6-phosphate receptor, MPR 300, CD222 antigen, IGF2R, MPRI

Target

FUNCTION: Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2.
SUBUNIT: Binds GGA1, GGA2 and GGA3.
SUBCELLULAR LOCATION: Lysosome membrane; Single-pass type I membrane protein.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Szebenyi G, et al. Genomics 19:120-129(1994).

Limitation

For research use only

Code

OSM00084W

$240USD

Unit size

100 µl

Conjugate

Unconjugated antibody

Host

NZ white rabbit

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB. A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity

Specific for MPRI.

Spcs X-react.

Mouse. Not yet tested in other species but expected to work in rat.

Format

Lyophilised

Reconstitution

Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OSM00084W