Roundabout homolog 1 antibody, Robo1 antibody

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSR00359W

$240USD

ID Tag

Rb1360-140310-WS

Immunogen

A synthetic peptide to from c-terminal region of mouse Robo1 (Roundabout homolog 1) conjugated to an immunogenic carrier protein was used as the antigen.

Accession

ROBO1_MOUSE

Also known

Roundabout homolog 1, Dutt1

Target

FUNCTION: Receptor for SLIT1 and SLIT2 which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex. May be required for lung development.
Subcellular location: Membrane; Single-pass type I membrane protein
Tissue specificity: Expressed in embryonal spinal chord. Expressed in embryonal lung, and in adult lung bronchial epithelial cells of large proximal airways.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Xian J, et al. Proc. Natl. Acad. Sci. U.S.A. 98:15062-15066(2001)
2. Long H, et al. Neuron 42:213-223(2004)
3. Sundaresan V, et al. Mol. Cell. Neurosci. 11:29-35(1998)
4. Yuan W, et al. Dev. Biol. 212:290-306(1999)
5. Yuasa-Kawada J, et al. Proc. Natl. Acad. Sci. U.S.A. 106:14530-14535(2009)

Limitation

For research use only

Code

OSR00359W

$240USD

Unit size

100 µl

Conjugate

Unconjugated antibody

Host

NZ white rabbit

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB. A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity

Specific for Robo1.

Spcs X-react.

Mouse. Other species not yet tested.

Format

Lyophilised

Reconstitution

Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OSR00359W