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Code
OSP00092W
$240USD
ID Tag
Rb1162-260909-WS
Immunogen
A synthetic peptide from the c-terminal region of human P2Y7 (LT4R1) conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
P2Y purinoceptor 7, Purinergic receptor, P2RY7, LTB4R, LT4R1, Leukotriene B4 receptor 1, LTB4-R 1, BLT, BLT1, BLTR, CMKRL1, GPR16
Target
FUNCTION: Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.
Tissue specificity: Expressed at highest levels in heart, skeletal muscle and at lower levels in brain and liver. High level of expression in lymphoid tissues.
Subcellular location: Membrane; Multi-pass membrane protein.
Tissue specificity: Expressed at highest levels in heart, skeletal muscle and at lower levels in brain and liver. High level of expression in lymphoid tissues.
Subcellular location: Membrane; Multi-pass membrane protein.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Akbar G.K.M, et al. J. Biol. Chem. 271:18363-18367(1996)
2. Gaudreau R, et al. J. Biol. Chem. 277:31567-31576(2002)
2. Gaudreau R, et al. J. Biol. Chem. 277:31567-31576(2002)
Limitation
For research use only
Code
OSP00092W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for P2RY7.
Spcs X-react.
Human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSP00092W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to P2RY7
