A synthetic peptide from human Bif conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and mouse.
SHLB1, SH3 domain-containing GRB2-like protein B1, Bax-interacting factor 1, Bif-1, SH3GLB1, Bif, Bif1, Bif 1
Function: May be required for normal outer mitochondrial membrane dynamics. Required for coatomer-mediated retrograde transport in certain cells. May recruit other proteins to membranes with high curvature. May promote membrane fusion.
Subcellular location: Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Mitochondrion outer membrane; Peripheral membrane protein. Note: Association with the Golgi apparatus depends on the cell type
Tissue specificity: Highly expressed in heart, skeletal muscle, kidney and placenta. Detected at lower levels in brain, colon, thymus, spleen, liver, small intestine, lung and peripheral blood leukocytes.
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
12 months after reconstitution
This item will be shipped to you at ambient temperature in a lyophilised form.
1. Cuddeback S.M, et al. J. Biol. Chem. 276:20559-20565(2001)
For research use only
NZ white rabbit
Polyclonal, whole serum
IHC, WB. A dilution of 1: 8000 is recommended for WB and 1:2000 for IHC-P. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specific for Bif-1.
Human, rat, mouse. Other species not yet tested.
Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.