P2Y12 antibody, P2RY12 antibody, Purinergic receptor 12 antibody, P2Y purinoceptor 12 antibody, HORK3 antibody

Primary Antibodies

Peptides

Histology / Detection

⚬ Services

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSP00065W

$240USD

ID Tag

Rb961-280609-WS

Immunogen

A synthetic peptide from the 4th cytoplasmic domain of human P2Y12 (P2RY12) conjugated to blue carrier protein was used as the antigen.

Accession

P2RY12_HUMAN

Also known

P2Y purinoceptor 12, P2RY12, Purinergic receptor 12, P2Y12 platelet ADP receptor, P2Y(ADP), ADP-glucose receptor, ADPG-R, P2Y(AC), P2Y(cyc), P2T(AC)

Target

FUNCTION: Receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. Not activated by UDP and UTP. Involved in platelets aggregation. Defects in P2RY12 are a cause of bleeding disorder.
Tissue specificity: Highly expressed in the platelets, lower levels in the brain. Lowest levels in the lung, appendix, pituitary and adrenal gland. Expressed in the spinal cord and in the fetal brain.
Subcellular location: Membrane; Multi-pass membrane protein.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Hollopeter G, et al. Nature 409:202-207(2001)

Limitation

For research use only

Code

OSP00065W

$240USD

Unit size

100 ul

Conjugate

Unconjugated antibody

Host

NZ white rabbit

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity

Specific for P2RY12.

Spcs X-react.

Human. Other species not yet tested.

Format

Lyophilised

Reconstitution

Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OSP00065W