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Code
OSC00149W
$240USD
ID Tag
Rb997-280609-WS
Immunogen
A synthetic peptide from the n-terminal region of rat Chloride channel protein ClC-Kb (CLCKB) conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
Chloride channel Kb, ClC-K2, CLCKB
Target
FUNCTION: Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport. May be important in urinary concentrating mechanisms.
Subcellular location: Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Note: Recruited to the plasma membrane in the presence of BSND protein, whereas remains in the Golgi in its absence.
Tissue specificity: Expressed predominantly in the kidney. Expressed in all segments of the nephron examined, including the S2 segment and the glomerulus.
Subcellular location: Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Note: Recruited to the plasma membrane in the presence of BSND protein, whereas remains in the Golgi in its absence.
Tissue specificity: Expressed predominantly in the kidney. Expressed in all segments of the nephron examined, including the S2 segment and the glomerulus.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Kieferle S, et al. Proc. Natl. Acad. Sci. U.S.A. 91:6943-6947(1994)
2. Hayama A, et al. Histochem. Cell Biol. 119:485-493(2003)
2. Hayama A, et al. Histochem. Cell Biol. 119:485-493(2003)
Limitation
For research use only
Code
OSC00149W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for CLCKB.
Spcs X-react.
Rat. Other species not yet tested but expected to work in mouse.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSC00149W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to CLCKB
