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Code
OSL00007W
$240USD
ID Tag
Rb880-290309-WS
Immunogen
A synthetic peptide from aa region 5-50 of mouse LATS2 conjugated to blue carrier protein was used as the antigen.
Accession
Also known
Serine/threonine-protein kinase LATS2, Large tumor suppressor homolog 2, Serine/threonine-protein kinase kpm, Kinase phosphorylated during mitosis protein
Target
FUNCTION: Tumor suppressor which plays a critical role in centrosome duplication, maintenance of mitotic fidelity and genomic stability. Negatively regulates G1/S transition by down-regulating cyclin E/CDK2 kinase activity. Negative regulator of the androgen receptor.
Subcellular location: Centrosome. Cytoplasm. Note: Co-localizes with STK6 at the centrosomes during interphase, early prophase and cytokinesis. Migrates to the spindle poles during mitosis, and to the midbody during cytokinesis.
Tissue specificity: Expressed at high levels in ovary and testis and at lower levels in all other tissues examined.
Subcellular location: Centrosome. Cytoplasm. Note: Co-localizes with STK6 at the centrosomes during interphase, early prophase and cytokinesis. Migrates to the spindle poles during mitosis, and to the midbody during cytokinesis.
Tissue specificity: Expressed at high levels in ovary and testis and at lower levels in all other tissues examined.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Yabuta N, et al. Genomics 63:263-270(2000)
Limitation
For research use only
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Code
OSL00007W
$240USD
Unit size
100 ul
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for LATS2.
Spcs X-react.
Mouse, human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSL00007W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
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Rabbit antibody to LATS2
