⚬ Services
Code
OSK00018G
$240USD    Buy Now 

ID Tag
Rb865-290309-G

Immunogen
A synthetic peptide from the cytoplasmic domain of human KCNJ3 (GIRK1, Kir3.1) conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in rat and mouse.

Accession

Also known
G protein-activated inward rectifier potassium channel 1, GIRK1, Potassium channel, inwardly rectifying subfamily J member 3, Inward rectifier K(+) channel Kir3.1

Target
FUNCTION: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.
Subcellular location: Membrane, Multi-pass membrane protein.

Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date
12 months after reconstitution

Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.

References
1. Partiseti M, et al. FEBS Lett. 434:171-176(1998)
2. Hejtmancik J.F, et al. Am. J. Hum. Genet. 82:174-180(2008)

Limitation
For research use only

Related
products
 
Code Product Name
OSK00017W Rabbit antibody to KCNJ3
 

Code
OSK00018G
$240USD    Buy Now 

Unit size
500 µg

Conjugate
Unconjugated antibody

Host
NZ white rabbit

Purity
IgG

Clonality
Polyclonal

Isotype
Polyclonal, IgG

Applications
IHC, WB. A concentration of 10-50 µg/ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

Specificity
Specific for KCNJ3.

Spcs X-react.
Human, rat, mouse. Other species not yet tested.

Format
Lyophilised

Reconstitution
Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.

Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

⚬ Products
Rabbit antibody to KCNJ3
Content

Download Protocols

APES coating of slides
Loading Buffer: Reducing
IHC-P on Autostainer
G1 Lysing Buffer
WB Protocol online
IHC-P HIER (Tris-EDTA, pH 9)
4% PFA
Davidson's fix (modified)
....Tissue lysate perparation
....G2 Lysing Buffer
....R Lysing Buffer
....G3 Lysing Buffer
....G4 Lysing Buffer
....G5 Lysing Buffer
....G6 Lysing Buffer
Content

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