A synthetic peptide from mouse VGLUT3 conjugated to blue carrier protein was used as the antigen.
Vesicular glutamate transporter 3, Solute carrier family 17 member 8
FUNCTION: Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate.
SUBCELLULAR LOCATION: Cytoplasmic vesicle âº secretory vesicle âº synaptic vesicle membrane. Membrane; Multi-pass membrane proteinPotential. Cell junction âº synapse âº synaptosome.
TISSUE SPECIFICITY: Expressed in brain, kidney and liver. Expressed within the amygdala, brainstem, cerberal cortex, dorsal root ganglia, dorsal spinal cord, hippocampus, hypothalamus, retina, striatum and ventral spinal cord. Expressed within neurons of the caudate-putamen, olfactory tubercle, nucleus accumbens, hippocampus, interpeduncular nucleus and dorsal and medial raphe nuclei. Expressed in inner hair cells of the ear. Expressed at synaptic terminals within the lateral superior olive (LSO), a nucleus of the mammalian sound localization system, and in the medial nucleus of the trapezoid body (MNTB), which provides inhibitory input to the LSO.
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
12 months after reconstitution
This item will be shipped to you at ambient temperature in a lyophilised form.
1. Schaefer M.K.-H, et al. J. Biol. Chem. 277:50734-50748(2002)
For research use only
NZ white rabbit
Polyclonal, whole serum
IHC, WB. A dilution of 1: 1000 is recommended for WB and 1:100 to 1:200 for IHC-P. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specific for VGLUT3.
Mouse, rat, human, marmoset. Other species not yet tested.
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.