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Code
OSH00009W
$240USD
ID Tag
Rb475-150608-WS
Immunogen
A synthetic peptide from aa region 1150-1200 of rat Huntingtin conjugated to an immunogenic carrier protein was used as the antigen. The peptide shares 87% identity with mouse and human sequences.
Accession
Also known
Huntington disease protein homolog, Htt, HD protein homolog
Target
FUNCTION: May play a role in microtubule-mediated transport or vesicle function.
SUBCELLULAR LOCATION: Cytoplasm. Nucleus.
TISSUE SPECIFICITY: Expressed to a high degree in all the regions of the brain of adults and in meiotic cells of the testis. In addition, very low levels are detected in various non-neuronal tissues (heart, muscle, liver, lung and kidney).
DEVELOPMENTAL STAGE: Identified at high levels in neuronal tissues of embryos as early as day 14.5. This expression remains constant in all further development stages (up to the adult). On the other hand the expression in non-neuronal tissues is down-regulated from stage 17.5 day old embryos.
SUBCELLULAR LOCATION: Cytoplasm. Nucleus.
TISSUE SPECIFICITY: Expressed to a high degree in all the regions of the brain of adults and in meiotic cells of the testis. In addition, very low levels are detected in various non-neuronal tissues (heart, muscle, liver, lung and kidney).
DEVELOPMENTAL STAGE: Identified at high levels in neuronal tissues of embryos as early as day 14.5. This expression remains constant in all further development stages (up to the adult). On the other hand the expression in non-neuronal tissues is down-regulated from stage 17.5 day old embryos.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Schmitt I, et al. Hum. Mol. Genet. 4:1173-1182(1995).
2. Strong T.V, et al. Nat. Genet. 5:259-265(1993).
2. Strong T.V, et al. Nat. Genet. 5:259-265(1993).
Limitation
For research use only
Related
products
products
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Code
OSH00009W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for Huntingtin.
Spcs X-react.
Rat, mouse. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSH00009W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
Code
OSH00009W
$240USD
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IF on 1 day- old mouse cortical cell culture using Rabbit antibody to Huntingtin at 1: 500 dilution. DAPI counter stained. |
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IF on 1 day- old mouse cortical cell culture using Rabbit antibody to Huntingtin at 1: 500 dilution. DAPI counter stained appearing in blue. |
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IF on 1 day- old mouse cortical cell culture using Rabbit antibody to Huntingtin at 1: 500 dilution. DAPI counter stained appearing in blue. |
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IF on 1 day- old mouse cortical cell culture using Rabbit antibody to Huntingtin at 1: 500 dilution. DAPI counter stained appearing in blue. |
⚬ Products
Rabbit antibody to Huntingtin (1150-1200)
