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Code
OSA00052W
$240USD    Buy Now 

ID Tag
Rb445-150608-WS

Immunogen
A synthetic peptide from the n-terminal of mouse DRAM (Damage-regulated autophagy modulator) conjugated to an immunogenic carrier protein has been used as the antigen. The peptide is homologous in rat and shares 86% identity with human's.

Accession

Also known
Damage-regulated autophagy modulator

Target
This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4.
FUNCTION: Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not involved in p73/TP73-mediated autophagy.
SUBCELLULAR LOCATION: Lysosome membrane; Multi-pass membrane protein.

Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date
12 months after reconstitution

Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.

References
1. Carninci P, et al. Science 309:1559-1563(2005).

Limitation
For research use only

Related
products
 
Code Product Name
OSD00012G Rabbit antibody to DRAM
 

Code
OSA00052W
$240USD    Buy Now 

Unit size
150 µl

Conjugate
Unconjugated antibody

Host
NZ white rabbit

Purity
Whole serum

Clonality
Polyclonal

Isotype
Polyclonal, whole serum

Applications
IHC, WB. Use at a dilution of 1 : 200 to 1 : 2000. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity
Specific for DRAM.

Spcs X-react.
Mouse, rat. Other species not yet tested.

Format
Lyophilised

Reconstitution
Reconstitute in 150 µl of sterile water. Centrifuge to remove any insoluble material.

Code
GSD00002P
$120USD   

ID Tag
50278-64

Unit size
50 µg

Accession

Also known
Damage-regulated autophagy modulator

Target
This is the immunising peptide for the products Rabbit antibody to DRAM (OSA00052W) and Rabbit antibody to DRAM (OSD00012G)

Purity
>93%

Applications
Control peptide

Format
Lyophilised

Reconstitution
This peptide is soluble in PBS and water.

Storage
Maintain refrigerated at 2-8°C for up to 12 months. After reconstitution keep at -20°C. Avoid freeze and thaw cycles.

Expiry Date
12 months after reconstitution

Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.

Limitation
For research use only

Related Products
OSA00052W,OSD00012G

Code
OSA00052W
$240USD    Buy Now 


Rabbit antibody to DRAM WB on PC12 cell lysate using Rabbit antibody to DRAM (OSA00052W) at 1 : 300 dilution. Pre-absorption of the antibody with the immunising peptide completely abolishes the detected band.

⚬ Products
Rabbit antibody to DRAM
Content

Download Protocols

APES coating of slides
Loading Buffer: Reducing
IHC-P on Autostainer
G1 Lysing Buffer
WB Protocol online
IHC-P HIER (Tris-EDTA, pH 9)
4% PFA
Davidson's fix (modified)
....Tissue lysate perparation
....G2 Lysing Buffer
....R Lysing Buffer
....G3 Lysing Buffer
....G4 Lysing Buffer
....G5 Lysing Buffer
....G6 Lysing Buffer
Content

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