Sh267-020217-G

A synthetic peptide from human cFos protein conjugated to blue carrier protein has been used as the antigen.

cFOS_HUMAN
cFOS_RAT
cFOS_MOUSE
cFOS_hamster
cFos_cat

Proto-oncogene protein cFOS

FUNCTION: Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation.
SUBUNIT: Heterodimer. Interacts with DSIPI; this interaction inhibits the binding of active AP1 to its target DNA. Interacts with MAFB
SUBCELLULAR LOCATION: Nucleus.
INDUCTION: C-fos expression increases upon a variety of stimuli, including growth factors, cytokines, neurotransmitters, polypeptide hormones, stress and cell injury.
SIMILARITY: Belongs to the bZIP family. Fos subfamily
SIMILARITY: Contains 1 bZIP domain

Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

12 months after reconstitution

This item will be shipped to you at ambient temperature in a lyophilised form.

1. van Straaten F, et al. Proc. Natl. Acad. Sci. U.S.A. 80:3183-3187(1983).

For research use only

500 ug

Unconjugated antibody

Sheep

IgG

Polyclonal

IgG

IHC, WB. Use at a concentration of 10-50 ug/ml. The optimal working concentration should be determined by the end user. Not yet tested in other applications.

Specific for cFos.

Human, rat, mouse, marmoset. Other species not yet tested.

Lyophilised

Reconstitute in 500 ul of sterile water. Centrifuge to remove any insoluble material.

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

- Click to download the Data Sheet

- Click to download the Material Safety Data Sheet