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Code
OSM00019A
$240USD    Buy Now 

ID Tag
MC192-131207-AP

Immunogen
Nerve growth factor receptor (TNFR superfamily, member 16)

Accession

Also known
TNR16, low-affinity nerve growth factor receptor, NGF receptor, Gp80-LNGFR, p75 ICD, low affinity neurotrophin receptor p75NTR, Tnfrsf16, Ngfr, p75, LNGFR, RNNGFRR

Target
FUNCTION: Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells.
SUBUNIT: Homodimer; disulfide-linked. Interacts with p75NTR-associated cell death executor. Interacts with NGFRAP1/BEX3. Interacts with TRAF2, TRAF4, TRAF6, PTPN13 and RANBP9. Interacts through TRAF6 with SQSTM1 which bridges NGFR to NTRK1. Interacts with BEX1.
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.

Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date
12 months after reconstitution

Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.

References
1. Sivilia S, et al. Histol. Histopathol. 23 (1), 1-10(2008).

Limitation
For research use only

Related
products

Code
OSM00019A
$240USD    Buy Now 

Unit size
100 ug

Conjugate
Unconjugated antibody

Host
Mouse

Purity
Affinity purified

Clonality
Monoclonal

Isotype
IgG1

Applications
WB, IHC, ELISA. A working concentration of 5-15 ug/ml is recommended. This antibody is suitable for use in paraformaldehyde fixed, alcohol fixed and paraffin-embedded sections. The optimal working solution should be determined by the end user.

Specificity
Specific for rat p75NTR.

Spcs X-react.
Rat

Format
Lyophilised

Reconstitution
Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.

Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code
OSM00019A
$240USD    Buy Now 


Mouse monoclonal antibody to rat p75NTR (MC192) IF on rat trigeminal using Mouse monoclonal antibody to rat p75NTR (OSM00019A) at a concentration of 10 µg/ml, Rabbit antibody to internal part of cFos  (OSC00040W) at 1 : 500 dilution and DAPI counterstained.
Mouse monoclonal antibody to rat p75NTR (MC192) IF on rat trigeminal using Mouse monoclonal antibody to rat p75NTR (OSM00019A) at a concentration of 10 µg/ml.
Mouse monoclonal antibody to rat p75NTR (MC192) IF on rat trigeminal using Mouse monoclonal antibody to rat p75NTR (OSM00019A) at a concentration of 10 µg/ml (green), Rabbit antibody to internal part of cFos (c-fos): whole serum (OSC00040W) at 1 : 500 dilution and DAPI counterstained appearing in blue.
Mouse monoclonal antibody to rat p75NTR (MC192) IF on rat olfactory bulb using Mouse monoclonal antibody to rat p75NTR (OSM00019A) at a concentration of 10 µg/ml.
Mouse monoclonal antibody to rat p75NTR (MC192) IF on rat olfactory bulb using Mouse monoclonal antibody to rat p75NTR (OSM00019A) at a concentration of 10 µg/ml (green), Rabbit antibody to internal part of cFos (c-fos): whole serum (OSC00040W) at 1 : 500 dilution and DAPI counterstained appearing in blue.
Mouse monoclonal antibody to rat p75NTR (MC192) IF on rat trigeminal using Mouse monoclonal antibody to rat p75NTR (OSM00019A) at a concentration of 10 µg/ml.
Mouse monoclonal antibody to rat p75NTR (MC192) IF on rat trigeminal using Mouse monoclonal antibody to rat p75NTR (OSM00019A) at a concentration of 10 µg/ml (green), Rabbit antibody to internal part of cFos (c-fos): whole serum (OSC00040W) at 1 : 500 dilution and DAPI counterstained appearing in blue.
Mouse monoclonal antibody to rat p75NTR (MC192) IF on rat olfactory bulb using Mouse monoclonal antibody to rat p75NTR (OSM00019A) at a concentration of 10 µg/ml.
Mouse monoclonal antibody to rat p75NTR (MC192) IF on rat olfactory bulb using Mouse monoclonal antibody to rat p75NTR (OSM00019A) at a concentration of 10 µg/ml (green), Rabbit antibody to internal part of cFos (c-fos): whole serum (OSC00040W) at 1 : 500 dilution and DAPI counterstained appearing in blue.
⚬ Products
Mouse monoclonal antibody to rat p75NTR (MC192)
Content

Download Protocols

APES coating of slides
SDS Loading Buffer
IHC-P on Autostainer
G1 Lysing Buffer
WB Protocol online
IHC-P HIER (Tris-EDTA, pH 9)
4% PFA
Davidson's fix (modified)
....Tissue lysate perparation
....G2 Lysing Buffer
....R Lysing Buffer
....G3 Lysing Buffer
....G4 Lysing Buffer
....G5 Lysing Buffer
.G6 Lysing Buffer
Content

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