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Code
OSS00420W
$240USD
ID Tag
Rb2404-170614-WS
Immunogen
A synthetic peptide from aa region 390-440 of mouse 5HT2B receptor conjugated to blue carrier protein was used as the antigen. The peptide shares 92% identity with human sequence and 82% with rat's.
Accession
Also known
5-hydroxytryptamine receptor 2B, 5-HT-2B, Serotonin receptor 2B, HTR2B
Target
FUNCTION: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Subcellular location: Cell membrane; Multi-pass membrane protein
Tissue specificity: Detected in most peripheral organs. Only low expression levels were found in the brain.
Subcellular location: Cell membrane; Multi-pass membrane protein
Tissue specificity: Detected in most peripheral organs. Only low expression levels were found in the brain.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Schmuck K, et al. FEBS Lett. 342:85-90(1994)
2. Choi D.S, et al. FEBS Lett. 352:393-399(1994)
2. Choi D.S, et al. FEBS Lett. 352:393-399(1994)
Limitation
For research use only
Code
OSS00420W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for 5HT2B receptor.
Spcs X-react.
Mouse. Other species not yet tested but expected to work in human and possibly rat.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSS00420W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to 5HT2B R (390-440)
