Anti TRPC3 antibody

Primary Antibodies

ABC Transporters

Autophagy

Cancer

Cellular

Immunology

Reporter Genes & Tags

Reproduction

SLC & Regulators

Subcellular Markers

Toxins

Peptides

Histology / Detection

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OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS
IMAGES

Code

OSR00065W

$240USD

ID Tag

Rb0619-170808-WS

Immunogen

A synthetic peptide from mouse TRPC3 conjugated to blue carrier protein was used as the antigen.
The location of the epitope is highlighted in green.

Accession

TRPC3_MOUSE

Also known

Short transient receptor potential channel 3, transient receptor potential cation channel, subfamily C, member 3, TrpC3, Transient receptor protein 3, Mtrp3, Receptor-activated cation channel TRP3, Trp-related protein 3, Trrp3, MGC124333

Target

FUNCTION: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C, and by inositol-1,4,5-triphosphate receptors (ITPR) with bound IP3. May also be activated by internal calcium store depletion.
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Abundantly expressed in brain. Concentrated in cerebellar Purkinje cells and sparsely localized in cerebellar granule lyer, pontine nuclei and thalamus. Lower levels detected in other tissues.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Mori Y, et al. NeuroReport 9:507-515(1998).

Limitation

For research use only

Code

OSR00065W

$240USD

Unit size

100 µl

Conjugate

Unconjugated antibody

Host

NZ white rabbit

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB. A dilution of 1 :1000 is recommended for WB and 1:500 for IHC-P. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity

Specific for TRPC3.

Spcs X-react.

Mouse, rat, marmoset. Other species not yet tested.

Format

Lyophilised

Reconstitution

Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OSR00065W