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Code
OSR00065W
$240USD    Buy Now 

ID Tag
Rb0619-170808-WS

Immunogen
A synthetic peptide from mouse TRPC3 conjugated to blue carrier protein was used as the antigen.
The location of the epitope is highlighted in green.

Accession

Also known
Short transient receptor potential channel 3, transient receptor potential cation channel, subfamily C, member 3, TrpC3, Transient receptor protein 3, Mtrp3, Receptor-activated cation channel TRP3, Trp-related protein 3, Trrp3, MGC124333

Target
FUNCTION: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C, and by inositol-1,4,5-triphosphate receptors (ITPR) with bound IP3. May also be activated by internal calcium store depletion.
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Abundantly expressed in brain. Concentrated in cerebellar Purkinje cells and sparsely localized in cerebellar granule lyer, pontine nuclei and thalamus. Lower levels detected in other tissues.

Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date
12 months after reconstitution

Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.

References
1. Mori Y, et al. NeuroReport 9:507-515(1998).

Limitation
For research use only

Code
OSR00065W
$240USD    Buy Now 

Unit size
100 µl

Conjugate
Unconjugated antibody

Host
NZ white rabbit

Purity
Whole serum

Clonality
Polyclonal

Isotype
Polyclonal, whole serum

Applications
IHC, WB. A dilution of 1 :1000 is recommended for WB and 1:500 for IHC-P. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity
Specific for TRPC3.

Spcs X-react.
Mouse, rat, marmoset. Other species not yet tested.

Format
Lyophilised

Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code
OSR00065W
$240USD    Buy Now 


Rabbit antibody to TRPC3 IF on mouse cerebellum (frozen section) at 1 : 500 dilution.
Rabbit antibody to TRPC3 IF on mouse cerebellum (frozen section) at 1 : 500 dilution.
Rabbit antibody to TRPC3 IF on mouse cerebellum (frozen section) at 1 : 500 dilution.
Rabbit antibody to TRPC3 IF on mouse cerebellum (frozen section) at 1 : 500 dilution.
⚬ Products
Rabbit antibody to TRPC3
Content

Download Protocols

APES coating of slides
Loading Buffer: Reducing
IHC-P on Autostainer
G1 Lysing Buffer
WB Protocol online
IHC-P HIER (Tris-EDTA, pH 9)
4% PFA
Davidson's fix (modified)
....Tissue lysate perparation
....G2 Lysing Buffer
....R Lysing Buffer
....G3 Lysing Buffer
....G4 Lysing Buffer
....G5 Lysing Buffer
....G6 Lysing Buffer
Content

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