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Code
OSC00287W
$240USD
ID Tag
Rb2016-200213-WS
Immunogen
A synthetic peptide from aa region 50-100 of human CBX1 conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
Chromobox protein homolog 1, HP1Hsbeta, Heterochromatin protein 1 homolog beta, HP1 beta, Heterochromatin protein p25, M31, Modifier 1 protein, p25beta
Target
FUNCTION: Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane.
SUBCELLULAR LOCATION: Nucleus. Note: Unassociated with chromosomes during mitosis.
Tissue specificity: Expressed in all adult and embryonic tissues.
SUBCELLULAR LOCATION: Nucleus. Note: Unassociated with chromosomes during mitosis.
Tissue specificity: Expressed in all adult and embryonic tissues.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Verschure P.J, et al. Mol. Cell. Biol. 25:4552-4564(2005)
Limitation
For research use only
Code
OSC00287W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB (confirmed by recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for CBX1.
Spcs X-react.
Human, mouse, rat. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSC00287W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to CBX1
