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Code
OSS00313W
$260USD    Buy Now 

ID Tag
Rb1500-130810-WS

Immunogen
A synthetic peptide from aa region 5-50 of extracellular domain of mouse SLC5A1 conjugated to blue carrier protein was used as the antigen. The peptide shares about 93% identity with rat sequence.

Accession

Also known
Solute carrier family 5 member 1, Sodium/glucose cotransporter 1, Na(+)/glucose cotransporter 1, High affinity sodium-glucose cotransporter, NAGT, SGLT1

Target
FUNCTION: Actively transports glucose into cells by Na+ cotransport with a Na+ to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na+/glucose cotransporter arranged in series along kidney proximal tubules.
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
Tissue specificity: Expressed mainly in intestine and kidney.
Involvement in disease: Defects in SLC5A1 are the cause of congenital glucose/galactose malabsorption (GGM). GGM is an intestinal monosaccharide transporter deficiency. It is an autosomal recessive disorder manifesting itself within the first weeks of life. It is characterized by severe diarrhea and dehydration which are usually fatal unless glucose and galactose are eliminated from the diet.

Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date
12 months after reconstitution

Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.

References
1. Lee W.S, et al. J. Biol. Chem. 269:12032-12039(1994)

Limitation
For research use only

Code
OSS00313W
$260USD    Buy Now 

Unit size
100 ul

Conjugate
Unconjugated antibody

Host
NZ white rabbit

Purity
Whole serum

Clonality
Polyclonal

Isotype
Polyclonal, whole serum

Applications
IHC, WB. A dilution of 1: 200 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity
Specific for SLC5A1.

Spcs X-react.
Mouse. Other species not yet tested but expected to work in rat.

Format
Lyophilised. This product contains 0.02% benzalkonium chloride.

Reconstitution
Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.

Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

⚬ Products
Rabbit antibody to SLC5A1
Content

Download Protocols

APES coating of slides
Loading Buffer: Reducing
IHC-P on Autostainer
G1 Lysing Buffer
WB Protocol online
IHC-P HIER (Tris-EDTA, pH 9)
4% PFA
Davidson's fix (modified)
....Tissue lysate perparation
....G2 Lysing Buffer
....R Lysing Buffer
....G3 Lysing Buffer
....G4 Lysing Buffer
....G5 Lysing Buffer
....G6 Lysing Buffer
Content

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