GIT2 antibody, ARF GTPase activating protein GIT2 antibody

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSG00076W

$240USD

ID Tag

Rb1601-120910-WS

Immunogen

A synthetic peptide from c-terminal region of mouse GIT2 (ARF GTPase-activating protein GIT2) conjugated to an immunogenic carrier protein was used as the antigen.

Accession

GIT2_MOUSE

Also known

ARF GTPase-activating protein GIT2, ARF GAP GIT2, Cool-associated and tyrosine-phosphorylated protein 2, CAT-2, CAT2, G protein-coupled receptor kinase-interactor 2, GRK-interacting protein 2

Target

FUNCTION: GTPase-activating protein for the ADP ribosylation factor family. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. GIT2 is implicated in the regulation of G protein coupled receptor sequestration, T cell activation, neuronal spine formation, and aggregate formation in Huntington's disease.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Bagrodia S, et al. J. Biol. Chem. 274:22393-22400(1999)
2. Villen J, et al. Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007)

Limitation

For research use only

Code

OSG00076W

$240USD

Unit size

100 µl

Conjugate

Unconjugated antibody

Host

NZ white rabbit

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB (confirmed by recombinant protein). A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user.

Specificity

Specific for GIT2.

Spcs X-react.

Mouse. Other species not yet tested.

Format

Lyophilised

Reconstitution

Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OSG00076W