KCC4 antibody, K-Cl cotransporter 4 antibody, SLC12A7 antibody

Primary Antibodies

ABC Transporters

Autophagy

Cancer

Cellular

Immunology

Reporter Genes & Tags

Reproduction

SLC & Regulators

Subcellular Markers

Toxins

Peptides

Histology / Detection

⚬ Services

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSS00290W

$240USD

ID Tag

Rb1533-130810-WS

Immunogen

A synthetic peptide from aa region 940-990 of human SLC12A7 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and mouse.

Accession

SLC12A7_HUMAN
SLC12A7_RAT
SLC12A7_MOUSE

Also known

Solute carrier family 12 member 7, Electroneutral potassium-chloride cotransporter 4, K-Cl cotransporter 4, SLC12A7

Target

Function: Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K⁺ uptake into Deiters' cells in the cochlea and contribute to K⁺ recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl^- extrusion in the kidney and contribute to renal acidification.
Tissue specificity: Detected in muscle, brain, lung, heart and kidney.
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Mount D.B, et al. J. Biol. Chem. 274:16355-16362(1999)
2. Mercado A, et al. J. Biol. Chem. 275:30326-30334(2000)

Limitation

For research use only

Code

OSS00290W

$240USD

Unit size

100 µl

Conjugate

Unconjugated antibody

Host

NZ white rabbit

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB (confirmed by recombinant protein). A dilution of 1: 200 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity

Specific for SLC12A7.

Spcs X-react.

Human, rat, mouse. Other species not yet tested.

Format

Lyophilised

Reconstitution

Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OSS00290W