A synthetic peptide from human Aquaporin 2 conjugated to blue carrier protein was used as the antigen.
Aquaporin-2, AQP-2, Aquaporin-CD, AQP-CD, Water channel protein for renal collecting duct, ADH water channel, Collecting duct water channel protein, WCH-CD, AQP2
FUNCTION: Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
Tissue specificity: Expressed in renal collecting tubules.
SUBCELLULAR LOCATION: Apical cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note: Shuttles from vesicles to the apical membrane.
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
12 months after reconstitution
This item will be shipped to you at ambient temperature in a lyophilised form.
1. Deen P.M.T, et al. Science 264:92-94(1994)
For research use only
Polyclonal, whole serum
IHC. (WB confirmed by recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specific for AQP2.
Human, rat, mouse. Other species not yet tested.
Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.