KCNU1 antibody, Slowpoke homolog 3 antibody, pH sensitive maxi potassium channel antibody

Primary Antibodies

ABC Transporters

Autophagy

Cancer

Cellular

G Protein Signaling

Hydra Proteins

Immunology

Ion Channels & pumps

Microbiology

Neuroscience

Reporter Genes & Tags

Reproduction

SLC & Regulators

Subcellular Markers

Toxins

Peptides

Histology / Detection

⚬ Services

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSP00130W

$240USD

ID Tag

Rb1552-290810-WS

Immunogen

A synthetic peptide from aa region 820-870 of mouse KCNU1 conjugated to blue carrier protein was used as the antigen.

Accession

KCNU1_MOUSE

Also known

Potassium channel subfamily U member 1, Calcium activated potassium channel subunit alpha 3, Calcium-activated potassium channel, subfamily M subunit alpha-3, Slowpoke homolog 3, Slo3, pH sensitive maxi potassium channel, KCNMA3

Target

FUNCTION: Testis-specific potassium channel activated by both intracellular pH and membrane voltage that mediates export of K⁺. May be involved in sperm capacitation and/or the acrosome reaction, essential steps in fertilization where changes in both intracellular pH and membrane potential are known to occur. In contrast to KCNMA1/SLO1, it is not activated by Ca²⁺ or Mg²⁺.
Subcellular location: Membrane; Multi-pass membrane protein
Tissue specificity: Testis-specific. Mainly expressed in spermatocytes.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Schreiber M, et al. J. Biol. Chem. 273:3509-3516(1998)

Limitation

For research use only

Related
products

Code	Product Name
OSP00136W	Rabbit antibody to KCNU1

Code

OSP00130W

$240USD

Unit size

100 ul

Conjugate

Unconjugated antibody

Host

NZ white rabbit

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB (confirmed by recombinant protein). A dilution of 1 : 3000 to 1 : 5000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity

Specific for KCNU1.

Spcs X-react.

Mouse. Other species not yet tested.

Format

Lyophilised

Reconstitution

Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OSP00130W