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Code
OSB00052W
$240USD
ID Tag
Rb1480-120610-WS
Immunogen
A synthetic peptide from aa region 2-35 of human BEX1 conjugated to blue carrier protein was used as the antigen.
Accession
Also known
BEX1, BEX2, HBEX2, HGR74-h
Target
FUNCTION: Signaling adapter molecule involved in p75NTR/NGFR signaling. Plays a role in cell cycle progression and neuronal differentiation. Inhibits neuronal differentiation in response to nerve growth factor (NGF). May act as a link between the cell cycle and neurotrophic factor signaling, possibly by functioning as an upstream modulator of receptor signaling, coordinating biological responses to external signals with internal cellular states.
SUBUNIT: Interacts with neurotrophin receptor p75NTR/NGFR. Interacts with OMP.
SUBCELLULAR LOCATION: Nucleus. Cytoplasm. Note: Shuttles between the cytoplasm and the nucleus.
TISSUE SPECIFICITY: Expressed in central nervous system, with high level in pituitary, cerebellum and temporal lobe. Expressed in lung, skeletal muscle, peripheral blood leukocyte, stomach, lymph node, trachea and bone marrow. Highly expressed in acute myeloid leukemia.
SUBUNIT: Interacts with neurotrophin receptor p75NTR/NGFR. Interacts with OMP.
SUBCELLULAR LOCATION: Nucleus. Cytoplasm. Note: Shuttles between the cytoplasm and the nucleus.
TISSUE SPECIFICITY: Expressed in central nervous system, with high level in pituitary, cerebellum and temporal lobe. Expressed in lung, skeletal muscle, peripheral blood leukocyte, stomach, lymph node, trachea and bone marrow. Highly expressed in acute myeloid leukemia.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Yang Q.-S, et al. Biochem. Genet. 40:1-12(2002).
2. Alvarez E, et al. Gene 357:18-28(2005).
2. Alvarez E, et al. Gene 357:18-28(2005).
Limitation
For research use only
Related
products
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Code
OSB00052W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 200 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for BEX1 (BEX2).
Spcs X-react.
Human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSB00052W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
Code
OSB00052W
$240USD
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IHC-P on paraffin sections of human tonsil. HIER: Tris-EDTA, pH 9 for 20 min using Thermo PT Module. Blocking: 0.2% LFDM in TBST filtered thru 0.2 µm. Detection was done using HRP polymer. Primary antibody: dilution 1: 1000, incubated 30 min at RT using Autostainer. Sections were counterstained with Harris Hematoxylin. |
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IHC-P on paraffin sections of human lymph node. HIER: Tris-EDTA, pH 9 for 20 min using Thermo PT Module. Blocking: 0.2% LFDM in TBST filtered thru 0.2 µm. Detection was done using HRP polymer. Primary antibody: dilution 1: 1000, incubated 30 min at RT using Autostainer. Sections were counterstained with Harris Hematoxylin. |
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IHC-P on paraffin sections of human bone marrow. HIER: Tris-EDTA, pH 9 for 20 min using Thermo PT Module. Blocking: 0.2% LFDM in TBST filtered thru 0.2 µm. Detection was done using HRP polymer. Primary antibody: dilution 1: 1000, incubated 30 min at RT using Autostainer. Sections were counterstained with Harris Hematoxylin. |
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Rabbit antibody to human BEX1 (2-35)
