A synthetic peptide from the c-terminal region of human AQP3 conjugated to blue carrier protein was used as the antigen.
Aquaporin-3, AQP-3, AQP3, Aquaporin 3, Aquaporin3
FUNCTION: Forms a water-specific channel that provide kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. May function as a water and urea exit mechanism in antidiuresis in collecting duct cells. Also slightly permeable to urea and glycerol. It may play an important role in gastrointestinal tract water transport and in glycerol metabolism.
Tissue specificity: Renal medulla and colon. Predominantly in the inner medulla.
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
12 months after reconstitution
This item will be shipped to you at ambient temperature in a lyophilised form.
1. Ishibashi K, et al. Genomics 27:352-354(1995)
For research use only
NZ white rabbit
Polyclonal, whole serum
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specific for AQP3.
Human. Other species not yet tested but expected to work in mouse.
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.