FPR2 antibody, Lipoxin A4 receptor antibody, FPRL1 antibody

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSF00007W

$240USD

ID Tag

Rb1252-051209-WS

Immunogen

A synthetic peptide from aa region 2-50 of human FPR2 conjugated to blue carrier protein was used as the antigen.

Accession

FPR2_HUMAN

Also known

N-formyl peptide receptor 2, FMLP-related receptor I, FMLP-R-I, Formyl peptide receptor-like 1, Lipoxin A4 receptor, LXA4 receptor, RFP, HM63, FPRH1, FPRL1, LXA4R

Target

FUNCTION: Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4).
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein
TISSUE SPECIFICITY: Expressed abundantly in the lung and neutrophils. Also found in the spleen and testis.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Bao L, et al. Genomics 13:437-440(1992)
2. Perez H.D, et al. Gene 118:303-304(1992)

Limitation

For research use only

Code

OSF00007W

$240USD

Unit size

100 µl

Conjugate

Unconjugated antibody

Host

NZ white rabbit

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity

Specific for FPR2.

Spcs X-react.

Human. Other species not yet tested.

Format

Lyophilised

Reconstitution

Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Code

OSF00007P

$120USD

ID Tag

81019-62

Unit size

50 Âµg

Accession

FPR2_HUMAN

Also known

N-formyl peptide receptor 2, FMLP-related receptor I, FMLP-R-I, Formyl peptide receptor-like 1, Lipoxin A4 receptor, LXA4 receptor, RFP, HM63, FPRH1, FPRL1, LXA4R

Target

This is the immunising peptide for the product Rabbit antibody to FPR2 (2-50) (OSF00007W)

Purity

>80%

Applications

Control peptide

Format

Lyophilised

Reconstitution

This peptide is soluble in DMF/DMSO.

Storage

Maintain refrigerated at 2-8°C for up to 12 months. After reconstitution keep at -20°C. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

Limitation

For research use only