Rb1177-260909-WS

A synthetic peptide from c-terminal region of human GRIK4 (EAA1, Glutamate receptor KA-1) conjugated to an immunogenic carrier protein was used as the antigen.

GRIK4_HUMAN
GRIK4_RAT
GRIK4_MOUSE

Glutamate receptor, ionotropic kainate 4, Glutamate receptor KA-1, KA1, Excitatory amino acid receptor 1, EAA1, GRIK

FUNCTION: Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists.
Subcellular location: Cell membrane; Multi-pass membrane protein. Cell junction › synapse › postsynaptic cell membrane; Multi-pass membrane protein.
Tissue specificity: Strong expression in hippocampal CA3 pyramidal cells. Low expression in hippocampal dentate granule cells, in layers II, V and VI of the cortex, and in cerebellar Purkinje cells. No expression in the striatum, reticular thalamus, hypothalamus or amygdaloid complex. Expressed at embryonic day 15 in brain and spinal cord. At embryonic day 19 expression accumulates in the hippocampal formation. Prominent expression in the subicular cortex at postnatal days P1, P8 and P15 but then markedly reduced in the adult.

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

12 months after reconstitution

This item will be shipped to you at ambient temperature in a lyophilised form.

1. Kamboj R.K, et al. J. Neurochem. 62:1-9(1994)
2. Ota T, et al. Nat. Genet. 36:40-45(2004)
3. Werner P, et al. Nature 351:742-744(1991)
4. Carninci P, et al. Science 309:1559-1563(2005)

For research use only

100 µl

Unconjugated antibody

NZ white rabbit

Whole serum

Polyclonal

Polyclonal, whole serum

IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specific for GRIK4.

Human. Other species not yet tested but expected to work in rat and mouse.

Lyophilised

Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

- Click to download the Data Sheet

- Click to download the Material Safety Data Sheet