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Code
OSS00194W
$240USD    Buy Now 

ID Tag
Rb1149-260909-WS

Immunogen
A synthetic peptide from c-terminal region of human 5HT3D receptor (Serotonin receptor 3D) conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in 5HT3E.

Accession

Also known
5-hydroxytryptamine receptor 3D, 5-HT3D, Serotonin receptor 3D, HTR3D; 5-hydroxytryptamine receptor 3E, 5-HT3E, Serotonin receptor 3E, HTR3E

Target
FUNCTION: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel.
Subcellular location: Cell membrane; Multi-pass membrane protein. Note: Presumably retained within the endoplasmic reticulum unless complexed with HTR3A.
Tissue specificity: 5HT3D: Expressed in liver, as well as fetal and adult colon and kidney. 5HT3E: Expressed in adult colon and intestine.

Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date
12 months after reconstitution

Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.

References
1. Niesler B, et al. Gene 310:101-111(2003)
2. Niesler B, et al. Mol. Pharmacol. 72:8-17(2007)
3. Karnovsky A.M, et al. Gene 319:137-148(2003)

Limitation
For research use only

Code
OSS00194W
$240USD    Buy Now 

Unit size
100 µl

Conjugate
Unconjugated antibody

Host
NZ white rabbit

Purity
Whole serum

Clonality
Polyclonal

Isotype
Polyclonal, whole serum

Applications
IHC, WB. A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity
Specific for 5HT3D, 5HT3E receptors.

Spcs X-react.
Human. Other species not yet tested.

Format
Lyophilised

Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

⚬ Products
Rabbit antibody to 5HT3D R / 5HT3E R
Content

Download Protocols

APES coating of slides
Loading Buffer: Reducing
IHC-P on Autostainer
G1 Lysing Buffer
WB Protocol online
IHC-P HIER (Tris-EDTA, pH 9)
4% PFA
Davidson's fix (modified)
....Tissue lysate perparation
....G2 Lysing Buffer
....R Lysing Buffer
....G3 Lysing Buffer
....G4 Lysing Buffer
....G5 Lysing Buffer
....G6 Lysing Buffer
Content

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