⚬ Services
Code
OSC00173W
$240USD    Buy Now 

ID Tag
Rb1047-020809-WS

Immunogen
A synthetic peptide from the n-terminal region of mouse CNG4 conjugated to an immunogenic carrier protein was used as the antigen.

Accession

Also known
CNGA4, cGMP-gated cation channel alpha-4, CNG-4, CNG4, Cyclic nucleotide-gated channel alpha-4, Cyclic nucleotide-gated channel, photoreceptor, Cyclic nucleotide gated cation channel 3, Cone photoreceptor cGMP-gated channel subunit alpha, CNCG4, CNG 4

Target
FUNCTION: Second messenger, cAMP, causes the opening of cation-selective cyclic nucleotide-gated (CNG) channels and depolarization of the neuron (olfactory sensory neurons, OSNs). CNGA4 is the modulatory subunit of this channel which is known to play a central role in the transduction of odorant signals and subsequent adaptation. By accelerating the calcium-mediated negative feedback in olfactory signaling it allows rapid adaptation to odor stimulation and extends its range of odor detection.
Tissue specificity: Olfactory neurons

Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date
12 months after reconstitution

Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.

References
1. Carninci P, et al. Science 309:1559-1563(2005)
2. Munger S.D, et al. Science 294:2172-2175(2001)

Limitation
For research use only

Code
OSC00173W
$240USD    Buy Now 

Unit size
100 µl

Conjugate
Unconjugated antibody

Host
NZ white rabbit

Purity
Whole serum

Clonality
Polyclonal

Isotype
Polyclonal, whole serum

Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity
Specific for CNGA4.

Spcs X-react.
Mouse, rat. Other species not yet tested.

Format
Lyophilised

Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

⚬ Products
Rabbit antibody to CNG4
Content

Download Protocols

APES coating of slides
SDS Loading Buffer
IHC-P on Autostainer
G1 Lysing Buffer
WB Protocol online
IHC-P HIER (Tris-EDTA, pH 9)
4% PFA
Davidson's fix (modified)
....Tissue lysate perparation
....G2 Lysing Buffer
....R Lysing Buffer
....G3 Lysing Buffer
....G4 Lysing Buffer
....G5 Lysing Buffer
.G6 Lysing Buffer
Content

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