⚬ Services
Code
OSC00159W
$240USD    Buy Now 

ID Tag
Rb1013-280609-WS

Immunogen
A synthetic peptide from aa region 2-50 of human CBY1 conjugated to an immunogenic carrier protein was used as the antigen.

Accession

Also known
Protein chibby homolog 1, PKD2 interactor, Golgi and endoplasmic reticulum-associated 1, PIGEA-14, Cytosolic leucine-rich protein, ARPP-binding protein, ARB1, CBY, PGEA1

Target
FUNCTION: Inhibits the Wnt/Wingless pathway by binding to beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation.
Tissue specificity: Widely expressed. Expressed at higher levels in heart, skeletal muscle, kidney and placenta. Also found in brain, lung, liver and testis. Significantly down-regulated in thyroid and metastatic uterine tumors.

Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date
12 months after reconstitution

Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.

References
1. Wiemann S, et al. Genome Res. 11:422-435(2001)
2. Collins J.E, et al. Genome Res. 13:27-36(2003)
3. Ota T, et al. Nat. Genet. 36:40-45(2004)
4. Dunham I, et al. Nature 402:489-495(1999)
5. Hidaka S, et al. J. Biol. Chem. 279:35009-35016(2004)

Limitation
For research use only

Code
OSC00159W
$240USD    Buy Now 

Unit size
100 µl

Conjugate
Unconjugated antibody

Host
NZ white rabbit

Purity
Whole serum

Clonality
Polyclonal

Isotype
Polyclonal, whole serum

Applications
IHC, WB. A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity
Specific for CBY1.

Spcs X-react.
Human, rat, mouse. Other species not yet tested.

Format
Lyophilised

Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

⚬ Products
Rabbit antibody to CBY1
Content

Download Protocols

APES coating of slides
Loading Buffer: Reducing
IHC-P on Autostainer
G1 Lysing Buffer
WB Protocol online
IHC-P HIER (Tris-EDTA, pH 9)
4% PFA
Davidson's fix (modified)
....Tissue lysate perparation
....G2 Lysing Buffer
....R Lysing Buffer
....G3 Lysing Buffer
....G4 Lysing Buffer
....G5 Lysing Buffer
....G6 Lysing Buffer
Content

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