AIPL1 antibody, Aryl hydrocarbon interacting protein like 1 antibody

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSA00100W

$240USD

ID Tag

Rb1059-020809-WS

Immunogen

A synthetic peptide from the internal region of human Aryl hydrocarbon interacting protein like 1 (AIPL1) conjugated to an immunogenic carrier protein was used as the immunogen.

Accession

AIPL1_HUMAN

Also known

Aryl-hydrocarbon-interacting protein-like 1, AIPL1

Target

Function: May be important in protein trafficking and/or protein folding and stabilization. Defects in AIPL1 are the cause of Leber congenital amaurosis type 4 (LCA4). LCA designates a clinically and genetically heterogeneous group of childhood retinal degenerations, generally inherited in an autosomal recessive manner. Affected infants have little or no retinal photoreceptor function as tested by electroretinography. LCA represents the most common genetic cause of congenital visual impairment in infants and children.
Subcellular location: Cytoplasm. Nucleus.
Tissue specificity: Highly expressed in retina. Specifically localized to the developing photoreceptor layer and within the photoreceptors of the adult retina.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Sohocki M.M, et al. Nat. Genet. 24:79-83(2000)
2. Ota T, et al. Nat. Genet. 36:40-45(2004)
3. Akey D.T, et al. Hum. Mol. Genet. 11:2723-2733(2002)

Limitation

For research use only

Code

OSA00100W

$240USD

Unit size

100 µl

Conjugate

Unconjugated antibody

Host

NZ white rabbit

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity

Specific for AIPL1.

Spcs X-react.

Human. Other species not yet tested.

Format

Lyophilised

Reconstitution

Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OSA00100W