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Code
OSP00074W
$240USD
ID Tag
Rb991-280609-WS
Immunogen
A synthetic peptide from the n-terminal of human KCNAB1 (Voltage-gated potassium channel subunit beta-1) conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known
Voltage-gated potassium channel subunit beta-1, KCNA1B, K(+) channel subunit beta-1, Kv-beta-1, KCAB1
Target
Function: Accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit. All three isoforms alter the functional properties of Kv1.4 and Kv1.5. Isoform KvB1.2 has no effect on Kv1.1, Kv1.2 or Kv2.1.
Tissue specificity: In brain, expression is most prominent in caudate nucleus, hippocampus and thalamus. Significant expression also detected in amygdala and subthalamic nucleus. Also expressed in both healthy and cardiomyopathic heart. Up to four times more abundant in left ventricle than left atrium.
Subcellular location: Cytoplasm
Tissue specificity: In brain, expression is most prominent in caudate nucleus, hippocampus and thalamus. Significant expression also detected in amygdala and subthalamic nucleus. Also expressed in both healthy and cardiomyopathic heart. Up to four times more abundant in left ventricle than left atrium.
Subcellular location: Cytoplasm
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. England S.K, et al. J. Biol. Chem. 270:28531-28534(1995)
2. Majumder K, et al. FEBS Lett. 361:13-16(1995)
2. Majumder K, et al. FEBS Lett. 361:13-16(1995)
Limitation
For research use only
Code
OSP00074W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for KCNAB1.
Spcs X-react.
Human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSP00074W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to KCNAB1
