⚬ Services
Code
OSE00024W
$240USD    Buy Now 

ID Tag
Sh168-280609-WS

Immunogen
A synthetic peptide from aa region 500-550 of rat SLC1A2 conjugated to an immunogenic carrier protein was used as the antigen. The antigen shares 95% identity with human and mouse sequence.

Accession

Also known
Sodium-dependent glutamate/aspartate transporter 2, GLUT-R, GLT-1, Solute carrier family 1 member 2, Slc1a2, Eaat2, Glt1

Target
Mediates dihydrokainate-sensitive glutamate transport; may play a role in presynaptic terminal glutamate transport and synaptic transmission.
FUNCTION: Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium.
SUBUNIT: Homotrimer. Interacts with JUB.
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Localized in brain and is highly enriched in the Purkinje cell layer in cerebellum, retina.

Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date
12 months after reconstitution

Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.

References
1. Pines G, et al. Nature 360:464-467(1992).
2. Kanner B.I, et al. FEBS Lett. 325:95-99(1993).

Limitation
For research use only

Code
OSE00024W
$240USD    Buy Now 

Unit size
100 µl

Conjugate
Unconjugated antibody

Host
Sheep

Purity
Whole serum

Clonality
Polyclonal

Isotype
Polyclonal, whole serum

Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity
Specific for EAAT2.

Spcs X-react.
Rat, mouse, human. Other species not yet tested.

Format
Lyophilised

Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

⚬ Products
Sheep antibody to SLC1A2 (500-550)
Content

Download Protocols

APES coating of slides
Loading Buffer: Reducing
IHC-P on Autostainer
G1 Lysing Buffer
WB Protocol online
IHC-P HIER (Tris-EDTA, pH 9)
4% PFA
Davidson's fix (modified)
....Tissue lysate perparation
....G2 Lysing Buffer
....R Lysing Buffer
....G3 Lysing Buffer
....G4 Lysing Buffer
....G5 Lysing Buffer
....G6 Lysing Buffer
Content

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