KCNMB4 antibody, BK channel subunit beta 4 antibody, Calcium activated potassium channel subunit beta 4 antibody

Primary Antibodies

ABC Transporters

Autophagy

Cancer

Cellular

G Protein Signaling

Hydra Proteins

Immunology

Ion Channels & pumps

Microbiology

Neuroscience

Reporter Genes & Tags

Reproduction

SLC & Regulators

Subcellular Markers

Toxins

Peptides

Histology / Detection

⚬ Services

OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS

Code

OSK00036W

$240USD

ID Tag

Rb907-260409-WS

Immunogen

A synthetic peptide from the c-terminal region of rat KCNMB4 (Maxi K channel subunit beta-4) conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in mouse.

Accession

KCNMB4_RAT
KCNMB4_MOUSE

Also known

Calcium-activated potassium channel subunit beta-4, Calcium-activated potassium channel, subfamily M subunit beta-4, Maxi K channel subunit beta-4, BK channel subunit beta-4, BKbeta4, K(VCA)beta-4, Slo-beta-4, Charybdotoxin receptor subunit beta-4

Target

Function: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Decreases the gating kinetics and calcium sensitivity of the KCNMA1 channel, but with fast deactivation kinetics. May decrease KCNMA1 channel openings at low calcium concentrations but increases channel openings at high calcium concentrations. Makes KCNMA1 channel resistant to 100 nM charybdotoxin (CTX) toxin concentrations
Subcellular location: Membrane, Multi-pass membrane protein.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Weiger T.M, et al. J. Neurosci. 20:3563-3570(2000)

Limitation

For research use only

Code

OSK00036W

$240USD

Unit size

100 µl

Conjugate

Unconjugated antibody

Host

NZ white rabbit

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity

Specific for KCNMB4.

Spcs X-react.

Rat, mouse. Other species not yet tested.

Format

Lyophilised

Reconstitution

Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OSK00036W